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Related Concept Videos

Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Role of Skin in Vitamin D Synthesis01:23

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

Lowering skin pH: improved barrier function, anti-ageing and beyond.

The British journal of dermatology·2018
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[Epidermal barrier disorders in dermatoses].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2016
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[Aged-related principles of topical therapy].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2014
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Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.

Skin pharmacology and physiology·2014
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Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor.

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Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.

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Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models
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[Aged skin and skin care].

E Proksch1

  • 1Klinik für Dermatologie, Venerologie und Allergologie, Univ.-Hautklinik, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstr. 7, 24105, Kiel, Deutschland, eproksch@dermatology.uni-kiel.de.

Zeitschrift Fur Gerontologie Und Geriatrie
|August 14, 2014
PubMed
Summary

Proper skin care is crucial for preventing and managing age-related skin diseases. Increased awareness and training for healthcare professionals are needed to improve outcomes for aged skin.

Area of Science:

  • Dermatology
  • Gerontology
  • Preventive Medicine

Context:

  • Aging skin results from chronological and UV-induced damage, leading to dryness, itching, and irregular pigmentation.
  • Light-exposed aged skin exhibits aesthetic concerns like roughness, scaliness, and uneven coloration.
  • Age-related skin conditions include eczema, skin cancer, irritant contact dermatitis, and pressure sores.

Purpose:

  • To provide an overview of common diseases affecting aged skin.
  • To outline prophylactic and therapeutic skin care strategies for preventing and reducing these conditions.
  • To highlight the knowledge gap among the elderly and healthcare professionals regarding effective aged skin management.

Summary:

  • Aged skin is susceptible to various diseases, including eczema and skin cancer, with delayed wound healing being common.

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  • Preventive and therapeutic skin care using appropriate creams and ointments can significantly improve aged skin conditions.
  • Low awareness and physical/mental limitations in older adults hinder adequate self-care, necessitating professional intervention.
  • Impact:

    • Highlights the need for enhanced training for healthcare professionals on the importance of skin care for the elderly.
    • Underscores the lack of sufficient research on the role of specific skin care regimens in managing age-related dermatological issues.
    • Emphasizes the potential for improved patient outcomes through better understanding and implementation of aged skin care practices.