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Updated: Apr 25, 2026
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric inflammatory pseudotumor: a case report and comprehensive literature review
Yusuf Yagmur1, Sami Akbulut, Serdar Gumus
1Department of Surgery, Diyarbakir Education and Research Hospital, 21400, Diyarbakir, Turkey.
Purpose:
This study aims to provide an overview of the literature on mesenteric/omental inflammatory pseudotumors (IPTs).
Methodology:
We present a new case of mesenteric IPT. We also conducted a systematic search of the English-language medical literature using PubMed, Medline, Google, and Google Scholar related to mesenteric or omental IPTs. The following search terms were used in various combinations: inflammatory myofibroblastic tumor, IPT, mesentery, and omentum. The search included articles published in the English language between January, 1978 and April, 2014. Studies were excluded if the full text was unavailable or missing information prohibited comparisons.
Results:
A total of 30 reports concerning 36 patients with inflammatory pseudotumors meeting the aforementioned criteria were included. The patients were aged from 10 months to 68 years (mean, 19.98 ± 20.5 years); 12 were female (16.75 ± 16.97 years; range, 10 months to 68 years) and 24 were male (21.6 ± 21.9 years; range, 18 months to 63 years). Detailed clinical and pathologic characteristics of 36 patients with IPTs are provided in Table 1.
Conclusion:
IPTs may be definitively diagnosed only by histopathological examination and are most effectively treated by resection with negative surgical borders. No consensus has yet been reached regarding when nonsurgical treatment options are most appropriate in management of these lesions. IPTs often recur locally, while distant metastases are very rare. Postoperative close surveillance is essential to detect recurrences early.
Insights
Inflammatory pseudotumors (IPTs) of the mesentery or omentum require histopathological diagnosis. Surgical resection with clear margins is the primary treatment, with close surveillance needed for potential local recurrence.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Mesenteric/omental inflammatory pseudotumors (IPTs) are rare neoplasms.
- Literature review to consolidate understanding of these rare tumors.
Observation:
- A systematic literature search identified 30 reports on 36 patients with mesenteric/omental IPTs.
- Patient age ranged from 10 months to 68 years, with a male predominance (24 males, 12 females).
Findings:
- Histopathological examination is crucial for definitive diagnosis of IPTs.
- Surgical resection with negative margins is the most effective treatment.
- IPTs have a high rate of local recurrence but rare distant metastasis.
Implications:
- Early and accurate diagnosis through histopathology is essential.
- Complete surgical resection is the cornerstone of effective IPT management.
- Postoperative surveillance is critical for detecting and managing recurrences promptly.
