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The medical mass spectrometer.

I E Sodal1

  • 1Paradygm Science and Technologies, Inc., Boulder, CO 80301.

Biomedical Instrumentation & Technology
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

Mass spectrometer technology precisely measures multiple gases quickly, advancing respiratory research. Now practical for clinical use, it enables noninvasive patient monitoring and cardiopulmonary diagnostics.

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Area of Science:

  • Analytical Chemistry
  • Medical Technology
  • Physiology

Background:

  • Mass spectrometers offer high-speed, precise measurement of numerous gas constituents.
  • Historically valuable in laboratory research for respiratory physiology discoveries.
  • Advancements in vacuum technology, electronics, and microprocessors enhance practicality.

Purpose of the Study:

  • To highlight the transition of mass spectrometer technology from laboratory to clinical settings.
  • To emphasize the role of mass spectrometry in noninvasive physiological monitoring.
  • To project the future significance of mass spectrometers in clinical patient monitoring.

Main Methods:

  • Utilizing the inherent specificity and sensitivity of mass spectrometers.
  • Developing and applying methods for noninvasive measurement of physiological parameters.

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  • Leveraging trace gas analysis capabilities.

    • Main Results:

    • Mass spectrometry has been instrumental in developing noninvasive measurement techniques in research.
    • The technology is now practical for clinical application due to engineering improvements.
    • Noninvasive methods for cardiac output and lung function are established.

    Conclusions:

    • Mass spectrometers are poised to become central to future noninvasive cardiopulmonary monitoring systems.
    • The technology's capabilities are crucial for routine clinical diagnostics.
    • Continued innovation will expand the role of mass spectrometry in patient care.