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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
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Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
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Aminophylline partially prevents the decrease of body temperature during laparoscopic abdominal surgery.

Dae Woo Kim1, Jung Ah Lee1, Hong Soo Jung1

  • 1Department of Anesthesiology and Pain Medicine, St. Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

Journal of Korean Medical Science
|August 15, 2014
PubMed
Summary
This summary is machine-generated.

Aminophylline effectively maintains core body temperature during laparoscopic surgery by inducing thermogenesis, even when peripheral vasoconstriction is reduced. This study demonstrates its potential to mitigate intraoperative hypothermia.

Keywords:
AminophyllineCore Body TemperatureThermogenic Effect

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Area of Science:

  • Anesthesiology
  • Pharmacology
  • Physiology

Background:

  • Aminophylline is known to induce thermogenesis and increase metabolic rate.
  • Intraoperative hypothermia is a common complication during laparoscopic surgery.
  • The effect of aminophylline on core body temperature during pneumoperitoneum is not well understood.

Purpose of the Study:

  • To investigate the effect of aminophylline on core body temperature during laparoscopic abdominal surgery requiring pneumoperitoneum.
  • To test the hypothesis that aminophylline reduces the change in core body temperature.

Main Methods:

  • Fifty patients were randomly assigned to receive either aminophylline or saline (control).
  • Esophageal and index finger temperatures were measured every 15 minutes during sevoflurane anesthesia.
  • Hemodynamic variables, including mean blood pressure and heart rate, were also monitored.

Main Results:

  • Patients receiving aminophylline maintained significantly higher esophageal temperatures at multiple time points (T45-T105) compared to the saline group.
  • Index finger temperatures were also significantly higher in the aminophylline group throughout the measurement period (T15-T105).
  • Aminophylline demonstrated a thermogenic effect, counteracting reduced peripheral thermoregulatory vasoconstriction.

Conclusions:

  • Aminophylline is effective in maintaining core body temperature during laparoscopic surgery.
  • The drug's thermogenic properties can mitigate intraoperative hypothermia.
  • Further research may explore optimal dosing and patient selection for aminophylline use in surgery.