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Osteosarcoma arising from the parapharyngeal space: A case report.
Manabu Hoshi1, Jun Takada1, Naoto Oebisu1
1Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.
Oncology Letters
|August 15, 2014
Summary
This study details a rare osteoblastic osteosarcoma in the parapharyngeal space, presenting the first computed tomography (CT) and magnetic resonance imaging (MRI) correlation. Imaging findings aid in diagnosing this rare tumor, with the patient responding to palliative treatment.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Osteosarcoma is a primary bone malignancy.
- The parapharyngeal space is an exceptionally rare site for osteosarcoma.
- This study addresses a unique case of osteoblastic osteosarcoma in this location.
Purpose of the Study:
- To report a rare case of osteoblastic osteosarcoma in the parapharyngeal space.
- To correlate imaging findings (CT and MRI) with pathological diagnosis.
- To discuss the diagnostic implications of such rare tumors.
Main Methods:
- Case presentation of a 56-year-old male with a parapharyngeal mass.
- Computed tomography (CT) and magnetic resonance imaging (MRI) for lesion characterization.
- Open biopsy for definitive histopathological diagnosis.
Main Results:
- Imaging revealed a heterogeneous parapharyngeal mass with ossification/calcification.
- Biopsy confirmed osteoblastic osteosarcoma with calcified malignant osteoid.
- Multiple lung metastases were identified on initial CT scan.
Conclusions:
- CT and MRI findings can suggest osteosarcoma in the parapharyngeal space.
- This rare tumor should be considered in the differential diagnosis for parapharyngeal masses with ossification.
- The patient received palliative chemotherapy and radiotherapy with a positive 24-month follow-up.
