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Published on: August 28, 2018
Comparison of 128-Slice Dual Source CT Coronary Angiography with Invasive Coronary Angiography
Rajneesh Madhok1, Abhinav Aggarwal2
1Professor, Department of Radiodiagnosis, Shri Ram Murti Smarak Institute of Medical Sciences , Bareilly, Uttar Pradesh, India .
Insights
128-slice dual-source CT coronary angiography offers accurate, non-invasive assessment of coronary artery disease (CAD). This advanced cardiac imaging technique provides high sensitivity and specificity, aiding in the diagnosis of CAD.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Coronary artery disease (CAD) is a leading cause of morbidity and mortality globally and in India.
- Invasive catheterization remains the gold standard for CAD evaluation.
- Advancements in cardiac imaging, such as 128-slice dual-source CT, are crucial for 21st-century diagnostics.
Purpose of the Study:
- To evaluate the diagnostic accuracy of 128-slice dual-source CT coronary angiography.
- To compare CT coronary angiography with conventional catheter coronary angiography.
Main Methods:
- Forty patients with suspected CAD underwent both CT coronary angiography and conventional catheter coronary angiography.
- Siemens 128-slice Dual Source Flash Definition CT scanner was utilized.
- Patient heart rates influenced the CT scanning mode (Retrospective or Prospective).
Main Results:
- A total of 600 out of 609 segments were assessable via CT coronary angiography.
- The study reported a specificity of 95.12%.
- Sensitivity and positive predictive value were 95.26% and 88.46%, respectively, with 21 false positives and 8 false negatives.
Conclusions:
- 128-slice dual-source CT scanner enables accurate non-invasive assessment of coronary artery disease.
- This technology presents a viable alternative to invasive diagnostic procedures for CAD.
Background:
Coronary artery disease (CAD) is one of the leading cause of the morbidity and mortality in India as well as worldwide and last decade has seen a steep rise in incidence of CAD in India. Direct visualization of the coronary arteries by invasive catheterization still represents the cornerstone of the evaluation of CAD. Cardiac imaging is a challenge of 21 (st) century and is being answered by 128 slice dual source CT as it has good temporal resolution, high scanning speed as well as low radiation dose.
Aim:
To assess the diagnostic accuracy of 128-slice dual source CT Cardiac Angiography in comparison with Conventional Catheter Cardiac Angiography.
Materials And Methods:
Forty patients attending the cardiology OPD with complaint of chest pain and suspected of having CAD were evaluated by CT coronary angiography and conventional invasive Catheter coronary angiography and the results were compared. All patients were checked for serum creatinine and ECG before the angiography. Computed Tomography (CT) coronary angiography was done using SIEMENS 128-slice Dual Source Flash Definition CT Scanner under either Retrospective or Prospective mode depending on the heart rate of the patient. Oral/IV beta-blocker were used whenever required.
Results:
Coronary arteries were assessed as per 17- segment AHA model. A total of 600/ 609 segments were evaluable in 40 suspected patients on CT coronary angiography, of which 21 were false positives and 8 were false negatives with specificity of 95.12% and sensitivity and positive predictive value of 95.26% & 88.46% respectively.
Conclusion:
Non-invasive assessment of CAD is now possible with high accuracy on 128-slice dual source CT scanner.
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