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Updated: Apr 25, 2026
Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Electrophysiological correlates of alcohol- and non-alcohol-related stimuli processing in binge drinkers: a follow-up
Géraldine Petit1, Charles Kornreich1, Bernard Dan1
1Laboratory of Psychological Medicine and Addictology, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Background:
The continuation of binge drinking is associated with the development of neurocognitive brain abnormalities similar to those observed in patients with alcohol dependence. Alcohol cue reactivity constitutes a risk marker for alcohol dependence. Through event-related potentials (ERPs), we aimed to examine its potential presence as well as its evolution over time in binge drinkers in a one-year period.
Methods:
ERPs were recorded during a visual oddball task in which controls (n=15) and binge drinkers (n=15) had to detect infrequent deviant stimuli (related or unrelated to alcohol) among frequent standard stimuli. The test was performed twice with a one-year interval in order to explore the long-lasting influence of drinking habits.
Results:
Contrary to the controls, binge drinkers showed significantly reduced amplitudes of the P1 component for both alcohol and non-alcohol-related cues and of the P3 component only for neutral cues in the second assessment compared with the first.
Conclusion:
The continuation of binge drinking over one year is associated with the development of brain functional abnormalities (indexed by the P1 component) as well as a higher reactivity to alcohol-related stimuli and/or a decreased reactivity to non-alcohol-related stimuli (indexed by the P3 component).
