Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

2.7K
In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
2.7K
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences01:20

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences

1.7K
Inductively coupled plasma–mass spectrometry (ICP–MS) is a highly selective and sensitive technique for accurate elemental analysis. Though the analysis of ICP–MS mass spectra is comparatively straightforward, it is affected by spectroscopic and non-spectroscopic interferences. Spectroscopic interferences arise when the plasma contains ionic species with an m/z value the same as the analyte ion. Spectroscopic interference can be categorized as isobaric, polyatomic ions, and...
1.7K
Atomic Emission Spectroscopy: Lab01:29

Atomic Emission Spectroscopy: Lab

866
AES is a powerful analytical technique, especially effective when used with plasma sources, producing abundant spectra in characteristic emission lines. The Inductively Coupled Plasma (ICP), in particular, yields superior quantitative analytical data due to its high stability, low noise, low background, and minimal interferences under optimal experimental conditions. However, newer air-operated microwave sources are emerging as promising alternatives that could be more cost-effective than...
866
Mass Analyzers: Overview01:13

Mass Analyzers: Overview

2.0K
The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermally symbiotic integration of osmotic membrane distillation and electrolysis for direct seawater hydrogen production.

Nature communications·2026
Same author

Urban ozone nonattainment: Interconnected challenges in the Intermountain Western U.S.

Journal of the Air & Waste Management Association (1995)·2026
Same author

Sequential Effect of Reaction Temperature on Physical and Chemical Properties of ZnO Nanoparticles for Water Purification in a Photocatalytic Reactor.

ACS omega·2026
Same author

Growth and formaldehyde degradation of photoheterotrophic <i>Methylobacterium</i> within radiation fogs.

mBio·2026
Same author

Ten questions concerning water quality in building hot water systems.

Building and environment·2026
Same author

Photosynthetic Diel Cycling Influences Inverse Zinc and Copper Solubility Dynamics within a Constructed Wetland.

Environmental science & technology·2026

Related Experiment Video

Updated: Apr 25, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
07:54

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials

Published on: October 27, 2020

4.0K

Nanoparticle size detection limits by single particle ICP-MS for 40 elements.

Sungyun Lee1, Xiangyu Bi, Robert B Reed

  • 1School of Sustainable Engineering and the Built Environment, Arizona State University , Tempe, Arizona 85287, United States.

Environmental Science & Technology
|August 15, 2014
PubMed
Summary
This summary is machine-generated.

This study presents a method to determine the smallest nanoparticle size detectable by single particle inductively coupled plasma mass spectrometry (spICP-MS) for 40 elements. This helps in accurately assessing nanoparticle performance, environmental fate, and health risks.

More Related Videos

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

6.7K
Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

12.8K

Related Experiment Videos

Last Updated: Apr 25, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
07:54

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials

Published on: October 27, 2020

4.0K
In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
14:53

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

Published on: February 3, 2018

6.7K
Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

12.8K

Area of Science:

  • Analytical Chemistry
  • Environmental Science
  • Materials Science

Background:

  • Accurate characterization of nano- to micro-size particles is crucial for manufacturing, environmental fate, and human health risk assessment.
  • Single particle inductively coupled plasma mass spectrometry (spICP-MS) quantifies metallic nanoparticles in aqueous matrices.
  • Knowledge of the size detection limit (Dmin) for various elements is needed to expand spICP-MS applications.

Purpose of the Study:

  • To develop and apply a method for estimating the size detection limit (Dmin) of spICP-MS for 40 different elements.
  • To identify elements and nanoparticles amenable to quantification by current spICP-MS techniques.

Main Methods:

  • Developed a method to estimate the size detection limit (Dmin) for spICP-MS.
  • Applied the method to nanoparticles composed of 40 elements.
  • Validated the Dmin estimation by comparing calculated values with literature data and experimental results.

Main Results:

  • Calculated Dmin values for 40 elements, showing substantial variation.
  • Elements like Ta, U, Ir, Rh, Th, Ce, and Hf exhibited the lowest Dmin (≤10 nm).
  • Elements such as Se, Ca, and Si showed high Dmin values (>200 nm).
  • Instrument sensitivity and nanoparticle density were found to significantly influence Dmin when background noise is low.

Conclusions:

  • The developed method accurately estimates spICP-MS size detection limits for various elements.
  • This work identifies elements suitable for spICP-MS quantification of small nanoparticles in aqueous media.
  • Understanding Dmin is essential for applying spICP-MS to assess nanoparticle performance, environmental transport, and health impacts.