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Updated: Apr 25, 2026
Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
miRNA panels as biomarkers for bladder cancer
Angelika Tölle1, Nadine Ratert, Klaus Jung
1Department of Urology, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany.
Aim:
Specific miRNA profiles have been identified for several samples from patients with bladder cancer. The results are not always congruent and partly contradictory. A comparison of published data was performed to select potential markers.
Materials & Methods:
A literature search in PubMed identified 79 articles published prior to June 2013. Reports regarding the detection of miRNAs in urine and blood have rarely been published; to date, nine respectively three articles are available.
Results:
The comparison of published data proved the utility of miRNAs as diagnostic and prognostic indicators of bladder cancer. In urine samples from bladder cancer patients, seven miRNAs were concordantly expressed with tumor tissues.
Conclusion:
Standardization is strictly required in pre-analytics and methods of miRNA measurements.
