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Updated: Apr 25, 2026
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Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations
Published on: August 21, 2018
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Acoustic devices for particle and cell manipulation and sensing
Yongqiang Qiu1, Han Wang2, Christine E M Demore3
1Institute for Medical Science and Technology, University of Dundee, 1 Wurzburg Loan, Dundee DD2 1FD, UK. y.qiu@dundee.ac.uk.
Sensors (Basel, Switzerland)
|August 16, 2014
Summary
Ultrasonic manipulation technology offers versatile, cost-effective cell and particle handling for microfluidics. This study details device development for precise 2D and 3D manipulation, aiding practical adoption.
Area of Science:
- Biotechnology
- Microfluidics
- Acoustic Manipulation
Background:
- Precise manipulation of cells and particles is crucial for cell biology and analytical chemistry.
- Existing technologies like optical tweezing have limitations.
- Ultrasonic manipulation offers advantages including versatility, low cost, and ease of integration.
Purpose of the Study:
- To review current ultrasonic manipulation technology.
- To report the development of ultrasonic standing wave manipulation devices.
- To explore electronically controlled 2D and 3D manipulation capabilities.
Main Methods:
- Development of simple devices with high-frequency ultrasonic transducers (>20 MHz).
- Design of complex ultrasonic transducer array systems.
- Computer simulations for device behavior prediction and experimental verification.
Main Results:
- Demonstrated feasibility of ultrasonic manipulation for biological cells and particles.
- Successful investigation of electronically controlled 2D and 3D manipulation.
- Characterization of piezoelectric and passive materials and fabrication techniques.
Conclusions:
- Ultrasonic manipulation technology is a promising tool for precise cell and particle handling in microfluidic systems.
- Further development can lead to low-cost, batch-producible devices for commercial applications.
- Addressing development challenges is key for long-term practical adoption.
