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A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Influence of body mass index on skin grafting in pediatric burns
Nicole E Sharp1, Priscilla G Thomas1, Ashley K Sherman1
1The Children's Mercy Hospital, Kansas City, MO, USA.
Insights
Underweight children with burns face higher skin grafting needs, while overweight children show a reduced requirement. This study clarifies body mass index impacts on pediatric burn treatment outcomes.
Area of Science:
- Pediatric Burn Care
- Body Mass Index (BMI) Research
- Grafting Utilization Studies
Background:
- Existing literature on body mass index (BMI) and burn outcomes in children is inconsistent.
- This study investigates the relationship between standardized pediatric BMI categories and skin graft utilization in burn patients.
Purpose of the Study:
- To analyze the impact of pediatric BMI categories on burn outcomes.
- To determine if body habitus influences the need for skin grafting in pediatric burn patients.
Main Methods:
- A retrospective chart review of pediatric patients treated for burns between January 1995 and November 2011.
- Categorization of Body Mass Index (BMI) using standard definitions: underweight (<5th percentile), normal (5th-85th percentile), overweight (85th-95th percentile), and obese (>95th percentile).
Main Results:
- Analysis included 1164 pediatric patients: 77 underweight, 604 normal weight, 215 overweight, and 268 obese.
- Underweight children had a nearly twofold increased risk of full-thickness burns and were 1.8 times more likely to require skin grafting.
- Overweight children showed a 23% decrease in skin grafting incidence compared to normal weight children, with no significant differences in Total Body Surface Area (TBSA) burned or grafted.
Conclusions:
- Pediatric burn patients who are underweight have a significantly higher likelihood of requiring skin grafting.
- Mildly overweight pediatric burn patients appear to have a protective effect against the need for skin grafting.
Background:
There is heterogeneous literature on the association of obese and underweight body habitus on burn outcomes in adult and pediatric literature. We examine the effect of standardized pediatric body mass index (BMI) categories skin graft utilisation.
Methods:
A retrospective chart review was performed on children who underwent burn treatment from January 1995 to November 2011. BMI was categorized by standard definitions: underweight (<5%), normal (5-85%), overweight (85-95%), obese (>95%).
Results:
There were 1164 patients: 77 underweight, 604 normal, 215 overweight, and 268 obese patients. No differences existed between group demographics. Grafts were performed in 39% of underweight, 27% of normal, 22% of overweight, and 27% of obese patients. Underweight children had nearly a 2 fold increase in their risk of full thickness burns and were 1.8 times more likely to undergo skin grafting than normal BMI children. Overweight children had a significant decrease in the incidence skin grafting by 23% then compared to normal weight children. There were no differences in percent TBSA burned or percent TBSA grafted using ANOVA.
Conclusions:
Underweight pediatric burn victims have an increased risk for skin grafting while mildly overweight children are slightly protected from skin grafting.
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