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Updated: Apr 25, 2026

Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats
Published on: February 8, 2022
[Testify patient's blood electrolyte concentration a tendency to approach that of replacement-fluid in continuous
Yunzhen Wu1, Chunting Wang, Guoliang Ren
1Department of Critical Care Medicine, Dongying People's Hospital, Dongying 257091, Shandong, China, Corresponding author: Wang Chunting, Department of Critical Care Medicine, Shandong Provincial Hospital, Jinan 250021, Shandong,
Objective:
To prove with mathematical formula that the patient's blood electrolyte concentration shows a tendency to approach that of replacement-fluid after continuous renal replacement therapy (CRRT).
Methods:
Electrolyte concentration of plasma, replacement-fluid and returning fluid were compared, and they were labeled as C(blood), C(norm), and C(return) respectively. The "C(return)" was calculated, and the relationship among them was demonstrated with comparison by mathematical formula. At last, according to their relationship, plasma change towards to the replacement fluid was analyzed.
Results:
It was showed that "C(blood)
Conclusions:
With mathematical model, it is proved that the replacement fluid electrolyte concentration is the final target of the plasma. We must make up the replacement fluid correctly. And this results provide the basis for CRRT treatment of electrolyte disorder.
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