Decrease of slow-wave sleep in children with prolonged absence of essential lipids intake
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Updated: Sep 25, 2026

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
Published on: October 11, 2018
I Fagioli1, P Baroncini, C Ricour
1INSERM U3, Paris.
Abstract:
Sleep measures of eight children fed by total parenteral nutrition (TPN) without essential lipids were compared to those of seven children fed by TPN receiving a daily supplementation of essential lipids. Slow wave sleep (SWS) is significantly decreased in the former group, particularly in the second half of the night, thus suggesting that lipids could be involved in sleep regulation.
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