Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

862
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
862
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

20
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
20
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

1.4K
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.4K
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

359
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
359
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

918
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
918
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

627
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
627

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mast Cells in Acute COVID-19 Patients.

Allergy·2026
Same author

Diagnostic value of blood culture growth patterns in distinguishing contaminants from pathogens.

Journal of clinical microbiology·2026
Same author

Improving blood culture procurement: a prospective 5-year hospital-wide study.

Israel journal of health policy research·2025
Same author

Response to comments on the article "Management of respiratory tract infection based on sputum culture results".

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2025
Same author

Management of respiratory tract infection based on sputum culture results.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2025
Same author

Epigenetic liquid biopsies reveal endothelial turnover and erythropoiesis in asymptomatic COVID-19.

Life science alliance·2025

Related Experiment Video

Updated: Apr 25, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

8.6K

Prosthetic valve endocarditis due to Streptococcus pneumoniae.

Ayman Natsheh1, Michal Vidberg2, Reuven Friedmann3

  • 1Department of Medicine B, Shaare Zedek Medical Center, Jerusalem, Israel.

Springerplus
|August 16, 2014
PubMed
Summary

Infective endocarditis caused by Streptococcus pneumoniae is rare today, even in older adults and those with prosthetic valves. Prompt antibiotic treatment leads to favorable outcomes, with no increased virulence observed.

Keywords:
Infective endocarditisMitral valve replacementProsthetic valve endocarditisStreptococcus pneumoniae

More Related Videos

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

14.6K
Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

5.8K

Related Experiment Videos

Last Updated: Apr 25, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

8.6K
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

14.6K
Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

5.8K

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Internal Medicine

Background:

  • Streptococcus pneumoniae (pneumococcus) historically caused up to 10% of infective endocarditis cases pre-antibiotics.
  • This association is now exceedingly rare in the current antibiotic era.

Purpose of the Study:

  • To report recent cases of pneumococcal endocarditis, particularly in elderly patients.
  • To assess the prevalence and outcomes of pneumococcal endocarditis, including prosthetic valve endocarditis (PVE).

Main Methods:

  • Retrospective case series of three patients diagnosed with S. pneumoniae endocarditis since 1997.
  • Literature review to identify additional cases of pneumococcal PVE.
  • Analysis of pneumococcal bacteremia data to estimate endocarditis prevalence.

Main Results:

  • Three elderly patients (>70 years) with S. pneumoniae endocarditis were treated successfully with antibiotics alone.
  • Pneumococcal endocarditis prevalence was 0.7% among patients >70 with pneumococcal bacteremia.
  • A literature review identified 16 additional PVE cases; overall, 76% of 17 patients survived, with 29% undergoing valve surgery.

Conclusions:

  • Pneumococcal endocarditis remains rare but treatable in the antibiotic era.
  • Outcomes are generally favorable, even in prosthetic valve endocarditis, with no evidence of increased virulence compared to other organisms.