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Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences

Laura M Cox1, Shingo Yamanishi2, Jiho Sohn2

  • 1Department of Microbiology, NYU Langone Medical Center, New York, NY 10016, USA; Department of Medicine, NYU Langone Medical Center, New York, NY 10016, USA.

Cell
|August 16, 2014
PubMed
Summary

Early-life antibiotic exposure, even at low doses, can permanently alter the gut microbiota, leading to lasting metabolic changes and increased obesity risk in hosts. These effects are mediated by the altered microbiota itself.

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