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Executive function late effects in survivors of pediatric brain tumors and acute lymphoblastic leukemia
Amanda L Winter1, Heather M Conklin, Vida L Tyc
1a Department of Pediatrics, Section of Psychology , Baylor College of Medicine , Houston , TX , USA.
Background:
Survivors of pediatric brain tumors (BT) and acute lymphoblastic leukemia (ALL) are at risk for neurocognitive late effects related to executive function.
Procedure:
Survivors of BT (48) and ALL (50) completed neurocognitive assessment. Executive function was compared to estimated IQ and population norms by diagnostic group.
Results:
Both BT and ALL demonstrated relative executive function weaknesses. As a group, BT survivors demonstrated weaker executive functioning than expected for age. Those BT survivors with deficits exhibited a profile suggestive of global executive dysfunction, while affected ALL survivors tended to demonstrate specific rapid naming deficits.
Conclusion:
Findings suggest that pediatric BT and ALL survivors may exhibit different profiles of executive function late effects, which may necessitate distinct intervention plans.
