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Birth weight reference percentiles for Chinese.

Li Dai1, Changfei Deng2, Yanhua Li3

  • 1National Center for Birth Defects Monitoring, West China Second University Hospital of Sichuan University, Chengdu, People's Republic of China; Key Laboratory of Obstetrics & Gynecology and Pediatric Diseases and Birth Defects of the Ministry of Education, West China Second University Hospital of Sichuan University, Chengdu, People's Republic of China.

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Summary
This summary is machine-generated.

Contemporary Chinese infants show increased birth weight percentiles compared to earlier data. This study provides an updated national reference for clinical and research use, reflecting changes since the 1980s.

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Area of Science:

  • Perinatology and Neonatology
  • Public Health and Epidemiology
  • Biostatistics

Background:

  • Accurate birth weight references are crucial for assessing fetal growth and neonatal health.
  • Previous references for Chinese infants may not reflect current population trends.
  • Changes in socioeconomic factors and healthcare likely influence birth weights.

Purpose of the Study:

  • To establish contemporary, population-based, gestational age-specific birth weight percentiles for Chinese infants.
  • To provide an updated national standard for clinical assessment and research.

Main Methods:

  • Utilized data from the China National Population-based Birth Defects Surveillance System (2006-2010).
  • Included 1,105,214 live singleton births (≥28 weeks gestation, no birth defects).
  • Employed the lambda-mu-sigma (LMS) method to generate percentile curves.

Main Results:

  • Developed separate gestational age-specific birth weight percentile curves for males and females.
  • Observed significant differences compared to historical Chinese and international references.
  • Indicated moderate increases in birth weight percentiles for both sexes across most gestational ages since the 1980s.

Conclusions:

  • Contemporary Chinese infants exhibit higher birth weight percentiles than previously documented.
  • An updated national reference is essential for accurate clinical interpretation and epidemiological studies.
  • These findings highlight the need for ongoing monitoring of infant growth trends.