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Early changes of myocardial deformation properties in patients with dystrophia myotonica type 1: a three-dimensional

Maurizio Galderisi1, Francesco De Stefano1, Ciro Santoro1

  • 1Hypertension Research Center, Department of Translational Medical Sciences, "Federico II" University Hospital, Naples, Italy.

International Journal of Cardiology
|August 16, 2014
PubMed
Abstract

No abstract available in PubMed .

Keywords:
CardiomyopathyMyotonic dystrophyReal time 3D echocardiographyStrainStroke volume

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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