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Related Experiment Video

Updated: Apr 25, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging

Published on: January 5, 2015

A fluorescence color-encoded lipid-supported polymeric particle.

Seung Won Shin¹, Kyung Soo Park², Changyoon Baek¹

¹School of Chemical Engineering, Sungkyunkwan University, Suwon 440-746, Gyeonggi-do, Republic of Korea.

Colloids and Surfaces. B, Biointerfaces

|August 16, 2014

Summary

Researchers developed a synthetic fluorescent particle for advanced cancer diagnostic imaging. This novel platform shows promise for both in vitro and in vivo applications in selective cancer detection.

Keywords:

Bio-inspirations Lipid-supported polymeric nanoarchitectures Nucleic acid–dye intercalations Selective cancer imagings

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Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy

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Published on: December 9, 2013

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Last Updated: Apr 25, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging

Published on: January 5, 2015

A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes

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Published on: December 13, 2019

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy

Published on: December 9, 2013

Area of Science:

Biomedical Engineering
Optical Imaging
Nanotechnology

Background:

Fluorescent and luminescent organisms are explored for novel imaging and diagnostics.
Existing biological imaging agents have limitations in specificity and application scope.

Purpose of the Study:

To design and develop a synthetic fluorescent light-encoding particulate.
To establish a novel platform for prospective cancer-diagnostic imaging.
To evaluate the efficacy of the particulate for selective cancer imaging.

Main Methods:

Synthesis of a novel fluorescent light-encoding particulate.
In vitro testing for selective cancer cell detection.
In vivo studies for cancer imaging applications.

Main Results:

Successful design and synthesis of the fluorescent particulate.
Demonstrated selective cancer diagnostic imaging capabilities.
Validated performance in both in vitro and in vivo models.

Conclusions:

The synthetic fluorescent particulate serves as a promising platform for cancer diagnostic imaging.
The developed particulate enables selective imaging for both in vitro and in vivo applications.
This approach offers a novel strategy for advancing cancer detection technologies.