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CT demonstration of cavernous sinus fat.

D D Stricof1, T O Gabrielsen, J T Latack

  • 1Department of Radiology, University of Michigan Hospital, Ann Arbor 48109.

AJNR. American Journal of Neuroradiology
|November 1, 1989
PubMed
Summary

Cavernous sinus fat deposits seen on CT scans are often normal, not exclusive signs of Cushing disease. This finding was observed in a significant portion of both Cushing disease and non-Cushing disease patients, suggesting it

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Area of Science:

  • Radiology
  • Endocrinology
  • Neurosurgery

Background:

  • Cavernous sinus fat deposits on CT scans have been considered an abnormal finding.
  • These deposits were previously thought to be a specific indicator of Cushing disease.

Purpose of the Study:

  • To evaluate the prevalence of cavernous sinus fat deposits in patients with and without Cushing disease.
  • To determine if cavernous sinus fat is a reliable sign of Cushing disease.

Main Methods:

  • Retrospective review of CT scans from 100 patients without Cushing disease and 10 patients with Cushing disease.
  • Analysis of the frequency of detectable cavernous sinus fat in both groups.

Main Results:

  • Twenty-seven percent of non-Cushing disease patients showed cavernous sinus fat.

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  • Forty percent of Cushing disease patients had detectable cavernous sinus fat.
  • The difference in prevalence between the groups was not statistically significant (p > 0.6).

    • Conclusions:

    • CT demonstration of cavernous sinus fat should generally be considered a normal finding.
    • Cavernous sinus fat deposits are not a specific sign of Cushing disease.