Related Experiment Video
Updated: Apr 25, 2026

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
Published on: October 6, 2017
Effective connectivity at synaptic level in humans: a review and future prospects
1Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey, onder.gurcan@ege.edu.tr.
Abstract:
Correct knowledge of the effective connectivity at the synaptic level in humans is a key prerequisite for increasing our understanding of the operation of the human central nervous system. Unfortunately, none of the current ambitious collaborative neuroscience projects pay enough attention to this topic and are thus unable to completely relate the microlevel properties of the system to its emergent macrolevel behaviors. In this review article, the problem of effective connectivity at the synaptic level in humans is explained, existing and possible computational approaches to fill explanatory gaps are reviewed, and the requisite characteristics of these approaches are considered.
More Related Videos
Related Concept Videos
Overview of Synapses
Integration of Synaptic Events
The Synapse
Electrical Synapses
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
Neuronal Communication
Synaptic Signaling
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...

