Present status of quinoxaline motifs: excellent pathfinders in therapeutic medicine
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Updated: Apr 25, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
1Department of Chemistry, School of Natural and Applied Sciences, College of Science and Technology, Covenant University, PMB 1023 Ota, Ogun State, Nigeria.
Abstract:
Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are complementary in shapes and charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be relatively easy to administer either as intramuscular solutions, oral capsules or rectal suppositories. This work deals with recent advances in the synthesis and pharmacological diversities of quinoxaline motifs which might pave ways for novel drugs development.
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