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Multicystic dysplastic kidney: a retrospective study

Sathish Sharada1, Mahalingam Vijayakumar, Prahlad Nageswaran

  • 1Departments of *Pediatrics and Pediatric Nephrology, Mehta Children's Hospital, Chetpet, Chennai, India. Correspondence to: Dr M Vijayakumar, Consultant Pediatric Nephrologist, Mehta Children's Hospital, No.2(e) Mc Nichols Road, 3rd Lane, Chetpet, Chennai 600 031, Tamilnadu, India. doctormvk@gmail.com.

Indian Pediatrics
|August 18, 2014
PubMed

Insights

Multicystic dysplastic kidney (MCDK) often resolves spontaneously in children. However, close pediatric nephrology follow-up is essential to monitor for renal structural and functional anomalies, including vesicoureteric reflux.

Area of Science:

  • Pediatric Nephrology
  • Medical Imaging
  • Urology

Background:

  • Multicystic dysplastic kidney (MCDK) is a common congenital anomaly.
  • Understanding the natural history and associated renal anomalies is crucial for management.

Purpose of the Study:

  • To describe the renal structural and functional anomalies in children diagnosed with MCDK.

Main Methods:

  • Retrospective analysis of 47 children with MCDK.
  • Data collected over a 6-year period from a pediatric nephrology unit.
  • Follow-up duration exceeded 12 months for 31 children.

Main Results:

  • Antenatal diagnosis in 72.3% of cases.
  • Spontaneous involution of MCDK observed in 68% of followed children.
  • Vesicoureteric reflux was the most common renal abnormality (28%); higher creatinine in contralateral reflux.
  • Sub-nephrotic proteinuria associated with involution; no hypertension, 6.4% renal failure.

Conclusions:

  • MCDK exhibits a high rate of spontaneous involution.
  • Vesicoureteric reflux and proteinuria are significant associated findings requiring monitoring.
  • Continuous pediatric nephrological surveillance is vital for children with MCDK.
Abstract

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