Clinical outcomes of transradial unprotected left main coronary artery stenting in the elderly
Qingsheng Wang1, Qiang Tan, Dongtian Liu
1Department of Cardiology, Qinhuangdao First Hospital, Hebei Medical University, Hebei, China. E-mail. qhdtanqiang@aliyun.com.
Insights
Transradial percutaneous coronary intervention (PCI) with drug-eluting stents is safe and effective for elderly patients with unprotected left main coronary artery disease, showing good long-term survival rates.
Area of Science:
- Cardiology
- Interventional Cardiology
- Geriatric Cardiology
Background:
- Unprotected left main coronary artery disease (ULMCA) poses significant risks, especially in elderly patients.
- Transradial approach (TRA) offers potential benefits for PCI procedures.
- Evaluating long-term outcomes of TRA-PCI in this specific high-risk population is crucial.
Purpose of the Study:
- To assess the long-term clinical outcomes of elderly patients (>70 years) undergoing transradial PCI with drug-eluting stents for ULMCA disease.
- To determine the safety and efficacy of this approach in a geriatric population.
Main Methods:
- A prospective study involving 79 elderly patients with ULMCA stenosis treated with drug-eluting stents via TRA.
- Data collection focused on major adverse cardiac events (MACE), including death, myocardial infarction, stroke, and target lesion revascularization.
- Follow-up duration was 3 years post-procedure.
Main Results:
- The 3-year MACE-free survival rate was 72.2%.
- Incidence of cardiac death was 7.6%, myocardial infarction was 5.1%, and target lesion revascularization was 13.9%.
- Advanced age and left main distal bifurcation involvement were identified as favorable predictors for MACE.
Conclusions:
- Transradial PCI with drug-eluting stents can achieve favorable angiographic and clinical results in elderly patients with ULMCA disease.
- The long-term survival data indicate that PCI via TRA is a safe and effective treatment option for ULMCA patients aged 70 years and older.
Objectives:
To evaluate the long-term results in elderly patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents for unprotected left main coronary artery disease by transradial approach.
Methods:
This study took place in Qinhuangdao First Hospital, Hebei Medical University, Hebei, China between October 2006 and December 2009. Seventy-nine elderly patients with unprotected left main coronary artery (ULMCA) stenosis, aged >70 years, that underwent drug-eluting stent were evaluated. The occurrence of major adverse cardiac events (MACE) (death, non-fatal myocardial infarction, stroke or target lesion revascularizations) was recorded after 3 years of follow-up.
Results:
After 3 years follow-up, the MACE free survival rate was 72.2%. Cardiac deaths occurred in 7.6% of patients. Myocardial infarction occurred in 5.1%, and target lesion revascularization in 13.9% of patients. Age and left main distal bifurcation were favorable predictors of MACE.
Conclusions:
Percutaneous coronary intervention can be performed with good angiographic and clinical results through a transradial approach in the elderly. The long term survival suggests that PCI in ULMCA patients ≥ 70 years is safe and efficacious.
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