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Related Experiment Videos

"Machineless" nutritional hemodialysis.

M Roberts1, M H Barney, M A Trott

  • 1Department of Nephrology, Sepulveda V.A. Medical Center, California 91343.

ASAIO Transactions
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

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Nutritional hemodialysis (NH) efficiently transfers glucose and amino acids to patients. This machineless approach offers a cost-effective, fail-safe alternative to intravenous nutrition, especially for acute renal failure patients.

Area of Science:

  • Nephrology
  • Nutritional Science
  • Biomedical Engineering

Background:

  • Nutritional hemodialysis (NH) is an adaptation of continuous arteriovenous hemodialysis (CAVHD).
  • Previous studies demonstrated efficient nutrient transfer from dialysate to patients using NH.
  • Low flux dialyzers and gravity systems showed feasibility for NH.

Purpose of the Study:

  • To investigate the feasibility of a machineless nutritional hemodialysis system.
  • To optimize nutrient delivery parameters for NH.
  • To evaluate NH as a cost-effective and safe alternative to parenteral nutrition.

Main Methods:

  • Prepared nutrient dialysate by adding glucose and amino acids to bicarbonate dialysate.
  • Eliminated bicarbonate dialysate by reducing volume and increasing glucose concentration.

Related Experiment Videos

  • Controlled dialysate flow and ultrafiltration using a postdialyzer valve and adjustable fluid container height.

    • Main Results:

    • Achieved 97% glucose transfer from dialysate to patient at 14.4 gm/dl glucose concentration and 3.9 ml/min outflow rate.
    • Demonstrated a gravity-based system is possible with low flux dialyzers.
    • NH proved to be as easy to perform as intravenous nutrition, less costly, and inherently fail-safe.

    Conclusions:

    • Machineless NH is a viable and efficient method for nutrient delivery.
    • NH offers a cost-effective, safe, and fluid-sparing alternative to intravenous nutrition.
    • Machineless NH and CAVHD could be crucial for managing acute renal failure patients post-disaster.