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Transgenerational epigenetics and brain disorders.

Nadia Rachdaoui1, Dipak K Sarkar1

  • 1Rutgers Endocrine Research Program, Department of Animal Sciences, Rutgers University, New Brunswick, New Jersey, USA.

International Review of Neurobiology
|August 19, 2014
PubMed
Summary

Transgenerational epigenetic inheritance, environmentally induced changes passed through generations, may explain brain disorder heritability. This review explores epigenetic mechanisms, particularly in fetal alcohol spectrum disorders.

Keywords:
DNA methylationGermlineHistoneInheritanceNeuronal diseaseTransgenerational

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