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Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line
Published on: September 13, 2024
[A painful occipital mass revealing a posterior encephalocele]
Sarah Meunier1, Sophie Michalak1, Julien Chaigneau1
1Département de pathologie cellulaire et tissulaire, CHU d'Angers, 4, rue Larrey, 49933 Angers, France.
Insights
Encephalocele, a neural tube defect, presents as a congenital malformation. This case highlights a posterior encephalocele in an infant, confirmed by pathological examination of the occipital mass.
Area of Science:
- Pediatric Pathology
- Developmental Biology
- Neuropathology
Background:
- Encephalocele is a congenital neural tube defect.
- It results from incomplete closure of the embryonic neural tube.
- Posterior encephalocele is a common form, involving protrusion of brain tissue through a skull defect.
Observation:
- A 7-month-old infant presented with a painful occipital mass present since birth.
- Pathological examination of the mass revealed mature brain and meningeal tissues.
- Tissues identified included neuroglia, ependymal canals, and meningothelial cells.
Findings:
- The pathological findings confirmed a diagnosis of encephalocele.
- The case illustrates a typical presentation of posterior encephalocele.
- Differential diagnoses for midline masses in infants were considered.
Implications:
- Accurate pathological diagnosis is crucial for managing neural tube defects.
- Understanding diverse presentations aids in identifying less common or 'aborted' forms.
- This case contributes to the understanding of encephalocele pathology and its variations.
Abstract:
Encephalocele is a congenital malformation caused by a neural tube defect during embryonic development. We report a case of posterior encephalocele in a 7-month-old infant with a painful occipital mass known since birth. Pathological examination of the mass showed different mature tissues derived from the brain and its coverings (e.g., neuroglia, ependymal canals and clusters of meningothelial cells). A diagnosis of encephalocele was made. The different forms of neural tube defect will be briefly discussed, especially the "aborted" forms (e.g., non-specific midline mass lesion or angioma) that the pathologist may encounter in his/her daily practice.
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