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Updated: Apr 25, 2026

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
Donor selection in heart transplantation
Ahmet Kilic1, Sitaramesh Emani1, Chittoor B Sai-Sudhakar1
11 The Department of Surgery, 2 The Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Insights
Selecting the right donor heart is crucial for successful heart transplantation. This review examines current guidelines and controversies in donor selection to improve patient survival and graft function.
Area of Science:
- Cardiology
- Transplant Surgery
- Medical Quality Improvement
Background:
- Increasing focus on healthcare quality, particularly heart transplant survival rates.
- Donor selection is a critical factor influencing transplant success.
Purpose of the Study:
- To review current guidelines for selecting donor hearts.
- To identify and discuss areas of controversy in donor selection.
- To optimize outcomes for heart transplant recipients.
Main Methods:
- Literature review of current guidelines.
- Analysis of controversial aspects in donor selection criteria.
- Synthesis of information to guide best practices.
Main Results:
- Established guidelines exist for donor heart selection.
- Several areas of controversy impact donor selection decisions.
- Inconsistent application of criteria can affect outcomes.
Conclusions:
- Appropriate donor selection is paramount for successful heart transplant programs.
- Addressing controversies in donor selection can enhance recipient survival.
- Adherence to optimized selection protocols improves graft function post-transplant.
Abstract:
There is increased scrutiny on the quality in health care with particular emphasis on institutional heart transplant survival outcomes. An important aspect of successful transplantation is appropriate donor selection. We review the current guidelines as well as areas of controversy in the selection of appropriate hearts as donor organs to ensure optimal outcomes. This decision is paramount to the success of a transplant program as well as recipient survival and graft function post-transplant.
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