Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise-induced hypercapnia in the horse.

W M Bayly1, D R Hodgson, D A Schulz

  • 1Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman 99164-6610.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|November 1, 1989
PubMed
Summary

Thoroughbred horses experience exercise-induced hypoxemia and CO2 retention during intense exercise due to high metabolic demands. Their respiratory system cannot fully compensate for the extreme gas exchange requirements, leading to impaired blood gas regulation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extracorporeal shockwave therapy raises mechanical nociceptive threshold in horses with thoracolumbar pain.

Equine veterinary journal·2019
Same author

Pharmacokinetics and safety of repeated oral dosing of acetaminophen in adult horses.

Equine veterinary journal·2019
Same author

PD-L1 and immune infiltrates are differentially expressed in distinct subgroups of gastric cancer.

Oncoimmunology·2019
Same author

Pharmacokinetics of firocoxib after intravenous administration of multiple consecutive doses in neonatal foals.

Journal of veterinary pharmacology and therapeutics·2017
Same author

Seroprevalence of Borrelia burgdorferi in Horses Presented for Coggins Testing in Southwest Virginia and Change in Positive Test Results Approximately 1 Year Later.

Journal of veterinary internal medicine·2016
Same author

Impact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer.

British journal of cancer·2015

Area of Science:

  • Equine physiology
  • Exercise science
  • Respiratory physiology

Background:

  • Thoroughbred horses exhibit exercise-induced pulmonary hemorrhage and impaired gas exchange.
  • Understanding blood gas regulation during exercise is crucial for equine athletic performance.

Purpose of the Study:

  • To investigate the effects of exercise intensity and duration on blood gases in thoroughbred horses.
  • To characterize exercise-induced failure in pulmonary gas exchange.

Main Methods:

  • Horses performed incremental exercise tests.
  • Arterial and mixed venous blood gases were measured.
  • Carbon dioxide production (VCO2) and breathing frequency (fb) were monitored.

Main Results:

Related Experiment Videos

  • Very heavy exercise led to increased PaCO2 and hypoxemia.
  • Hypoxemia was linked to absent hyperventilation and increased alveolar-arterial PO2 difference.
  • Prolonged intense exercise caused metabolic acidosis and decreased PaCO2 due to increased tidal volume.

Conclusions:

  • Horses do not achieve compensatory hyperventilation during very heavy exercise due to extreme metabolic rates.
  • CO2 retention occurs during short-term high-intensity exercise despite no apparent mechanical limitation.