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Wounds in patients with HIV.

Alexander McMeeking1, In Kim, Frank Ross

  • 1Alexander McMeeking, MD, is an Associate Professor of Medicine, New York University Langone Medical Center, New York, New York. In Kim, BS, is a medical student at New York University School of Medicine, New York. Frank Ross, MD, is an Assistant Professor of Surgery at New York University School of Medicine, New York. Elizabeth A. Ayello, PhD, RN, ACNS-BC, CWON, ETN, MAPWCA, FAAN, is Faculty, Excelsior College, School of Nursing, Albany, New York. Harold Brem, MD, FACS, is Chief, Division of Wound Healing and Regenerative Medicine, Winthrop University Hospital, Mineola, New York. Patrick Linton, MD, is Faculty, New York University Langone Medical Center, New York. Daniel K. O'Neill, MD, is Associate Director, Adult Offsite Anesthesia Services, New York University Langone Medical Center, New York. Dr Ayello has disclosed that she is a member of the board of the World Council of Enterostomal Therapists; is a consultant to Calmoseptine; was a consultant to Coloplast, Smith & Nephew, and Mölnlycke; is a member of the speakers' bureau for Hill-Rom; was a member of the speakers' bureau for PharMerica and Healthpoint; is remunerated by Hill-Rom for educational presentations; and is remunerated as Course Coordinator by the International Interprofessional Wound Care Course at New York University Langone Medical Center. Dr Brem has disclosed that his institution has received grant funding from the National Institutes of Health and National Institutes of Diabetes and Digestive and Kidney Diseases.

Advances in Skin & Wound Care
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PubMed
Summary

Highly active antiretroviral therapy (HAART) improves outcomes for HIV-positive patients. This study found a higher prevalence of venous ulcers and a lower prevalence of pressure ulcers in HIV-positive individuals compared to controls.

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Area of Science:

  • Medical research
  • Clinical epidemiology
  • HIV/AIDS studies

Background:

  • Highly active antiretroviral therapy (HAART) has significantly improved health outcomes for individuals with HIV.
  • Understanding the specific health challenges, such as skin conditions, in this population remains crucial.

Purpose of the Study:

  • To compare the prevalence of different types of skin ulcers between HIV-positive and HIV-negative individuals.
  • To investigate potential associations between HIV status and the occurrence of venous versus pressure ulcers.

Main Methods:

  • Retrospective data review of patient cohorts.
  • Subjects were stratified by HIV status (seropositive vs. seronegative).
  • Cohorts were matched for age and gender to control for confounding factors.

Main Results:

  • A higher fraction of venous ulcers was observed in the HIV-positive cohort.
  • A lower fraction of pressure ulcers was noted in the HIV-positive cohort compared to controls.
  • The findings suggest a differential prevalence of ulcer types based on HIV status.

Conclusions:

  • HIV status may be associated with a different risk profile for developing specific types of skin ulcers.
  • Further research is warranted to elucidate the mechanisms underlying the observed differences in ulcer prevalence.
  • Clinical awareness of these potential disparities can inform patient care and prevention strategies.