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Actinomycotic mastoiditis complicated by sigmoid sinus thrombosis and labyrinthine fistula
Cecilia Lezcano1, Jeffrey P Simons, Kathryn L Colman
11 Department of Pathology, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Abstract:
Actinomyces is a rare pathogen that can be the cause of infections in the digestive and urinary tracts, skin, genitalia, and lungs, which generally have an indolent clinical course. However, in some cases these can be locally destructive and become generalized infections. Actinomyces has been previously implicated in infections of the middle ear, nasopharynx, and sinuses, occasionally causing complications such as chronic mastoiditis. Here we describe the case of a 10-year-old-male presenting with nausea, vomiting, and headache who developed intracranial complications of actinomycotic mastoiditis.
Insights
Actinomyces infections are rare but can cause serious complications. This case highlights intracranial complications arising from actinomycotic mastoiditis in a pediatric patient.
Area of Science:
- Medical microbiology
- Infectious diseases
- Otolaryngology
Background:
- Actinomyces are unusual pathogens causing indolent infections in various body sites.
- While typically localized, Actinomyces infections can become destructive and systemic.
- Actinomycotic infections of the head and neck, including mastoiditis, are infrequently reported.
Observation:
- A 10-year-old male presented with nausea, vomiting, and headache.
- The patient developed intracranial complications secondary to actinomycotic mastoiditis.
Findings:
- This case details the progression of actinomycotic mastoiditis to severe intracranial complications.
- The clinical presentation underscores the potential severity of Actinomyces infections.
Implications:
- Highlights the importance of considering Actinomyces in refractory or unusual head and neck infections.
- Emphasizes the need for prompt diagnosis and management of actinomycotic mastoiditis to prevent neurological sequelae.
- Contributes to the understanding of rare infectious etiologies of intracranial complications.
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