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Acute epididymo-orchitis caused by Pseudomonas aeruginosa and treated with ciprofloxacin

H Humphreys1, D C Speller

  • 1Department of Microbiology, Bristol Royal Infirmary, U.K.

The Journal of Infection
|November 1, 1989
PubMed

Insights

Acute epididymo-orchitis caused by Pseudomonas aeruginosa is rare and challenging in elderly patients. Ciprofloxacin demonstrated effectiveness, leading to clinical cure in all cases and bacterial eradication in most.

Area of Science:

  • Urology
  • Infectious Diseases
  • Pharmacology

Background:

  • Acute epididymo-orchitis is an inflammation of the epididymis and testis.
  • Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe infections.
  • Elderly patients with genitourinary disease are particularly vulnerable to complicated infections.

Observation:

  • Three elderly patients with pre-existing genitourinary conditions presented with acute epididymo-orchitis.
  • The causative agent identified in all cases was Pseudomonas aeruginosa.
  • Treatment with ciprofloxacin was initiated due to its favorable pharmacokinetic properties.

Findings:

  • Ciprofloxacin therapy resulted in clinical cure for all three patients.
  • Pseudomonas aeruginosa was eradicated in two out of the three patients.
  • The study highlights ciprofloxacin's potential in managing difficult P. aeruginosa infections.

Implications:

  • Ciprofloxacin may be a viable treatment option for acute epididymo-orchitis caused by Pseudomonas aeruginosa, especially in elderly patients.
  • Early diagnosis and appropriate antibiotic selection are crucial for favorable outcomes.
  • Further research is warranted to confirm the efficacy and optimal dosing of ciprofloxacin in this patient population.

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