Related Experiment Video
Updated: Apr 25, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
Cerebrospinal fluid pressure in adults
Sarah C M Lee1, Christian J Lueck
1Department of Neurology (SCML, CJL), The Canberra Hospital, Canberra, Australia; Department of Neuroscience (SCML), Box Hill Hospital, Box Hill, Australia; and Australian National University Medical School (CJL), Canberra, Australia.
Lumbar puncture (LP) measures intracranial pressure (ICP) for diagnosis. Normal ICP in adults is 6-25 cmH2O, but clinical context is crucial due to individual variability.
Area of Science:
- Neurology
- Ophthalmology
- Neurosurgery
Background:
- Lumbar puncture (LP) is a key diagnostic tool for measuring intracranial pressure (ICP).
- Accurate ICP measurement is vital for patient diagnosis and management.
- Understanding factors influencing LP results is essential for clinical practice.
Purpose of the Study:
- To provide neuro-ophthalmologists with current information on factors affecting LP pressure measurements.
- To clarify the normal range of ICP and its variability.
- To emphasize the importance of clinical context in interpreting LP results.
Main Methods:
- Comprehensive literature review using PubMed and Medline.
- Scanning of relevant medical journals for recent publications.
- Secondary referencing and consultation with clinicians.
Main Results:
- The normal opening pressure range for ICP via LP in adults is 6 to 25 cmH2O.
- The population mean ICP is approximately 18 cmH2O.
- Significant individual variability exists, with some normal individuals exhibiting pressures above 30 cmH2O.
Conclusions:
- ICP measurements from LP require careful interpretation within the patient's clinical context.
- Awareness of factors influencing LP is critical for accurate diagnosis.
- This review offers updated insights for neuro-ophthalmologists performing and interpreting LPs.
More Related Videos
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...

