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Updated: Apr 25, 2026

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Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
Published on: February 9, 2019
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Optical coherence tomography technologies: which machine do you want to own?
1Departments of Clinical Neurosciences and Surgery, University of Calgary, Calgary, Alberta, Canada.
Summary
Optical coherence tomography (OCT) is a key ophthalmic imaging tool. It provides detailed retinal images, aiding in understanding neural pathway integrity and brain injury mechanisms.
Area of Science:
- Ophthalmology
- Neuroscience
- Medical Imaging
Background:
- Optical coherence tomography (OCT) has become a vital diagnostic tool in ophthalmology over the last decade.
- It is a noninvasive imaging technique offering high-resolution, cross-sectional views of ocular structures.
Purpose of the Study:
- To highlight the significance of OCT in ophthalmic practice.
- To underscore its role in assessing neural integrity and understanding brain injury.
Main Methods:
- Utilizing OCT to obtain detailed images of the retinal nerve fiber layer (RNFL).
- Analyzing cross-sectional images of the macular region, ganglion cell layer, and optic nerve head.
Main Results:
- OCT provides crucial data on axonal-neuronal integrity in the anterior visual pathway.
- The technique offers insights into the mechanisms of brain injury in CNS disorders.
Conclusions:
- OCT is an indispensable noninvasive imaging technique in modern ophthalmology.
- It significantly contributes to the understanding of neurological conditions through ocular assessment.
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