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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Severe infective endocarditis after MitraClip implantation treated by cardiac surgery
Christian Frerker1, Karl-Heinz Kuck, Tobias Schmidt
1Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Aims:
To report the first described case of a mitral valve infective endocarditis (IE) post MitraClip®.
Methods And Results:
An 88-year-old patient at high surgical risk (log. EuroSCORE 30.4%) underwent a MitraClip procedure for severe eccentric organic mitral regurgitation (MR) due to prolapse with a flail leaflet of the P2 segment (flail gap 6 mm). After one month, the patient was readmitted to our department for fever and recurrence of shortness of breath. An echocardiogram demonstrated severe MR recurrence due to ulceration in the region of the posterior leaflet despite good insertion of both clips, and a large vegetation of 1513 mm within the clip region. Blood cultures were positive for staphylococcus aureus. The patient was treated by cardiac surgery with mitral valve replacement due to IE despite a very high logistic EuroSCORE of 56.8%. Histological and bacteriological analysis of the clip devices confirmed active IE. After cardiac surgery, transthoracic echocardiography showed no mitral regurgitation and a mean gradient across the mitral valve bioprosthesis of about 5 mmHg. The patient was discharged to a rehabilitation department 15 days after cardiac surgery.
Conclusions:
Surgical treatment as bail-out therapy for MR recurrence secondary to IE after MitraClip can be successfully carried out despite a high surgical risk.
Insights
This case report details the first instance of infective endocarditis (IE) following a MitraClip procedure. Surgical intervention for recurrent mitral regurgitation (MR) due to IE proved successful, even in high-risk patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- MitraClip® is a device used to treat mitral regurgitation (MR).
- Infective endocarditis (IE) is a rare but serious complication following cardiac procedures.
- High surgical risk patients often benefit from less invasive procedures like MitraClip®.
Observation:
- An 88-year-old patient with severe MR underwent MitraClip® implantation.
- One month post-procedure, the patient presented with fever and dyspnea, indicating recurrent MR and suspected IE.
- Echocardiography revealed vegetation and ulceration in the clip region, with positive blood cultures for Staphylococcus aureus.
Findings:
- The patient underwent successful mitral valve replacement due to IE, despite a high logistic EuroSCORE.
- Histological analysis confirmed active IE on the clip devices.
- Post-surgery, the patient showed no mitral regurgitation and a favorable mitral valve bioprosthesis gradient.
Implications:
- Mitral valve replacement can be a viable bail-out strategy for IE after MitraClip®.
- Successful surgical outcomes are achievable even in extremely high-risk patients.
- This case highlights the importance of vigilance for IE post-MitraClip® procedures.
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