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Related Experiment Video

Updated: Jul 23, 2026

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

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Published on: September 20, 2015

Susceptibility-weighted imaging in heat stroke.

Xue-yan Zhang¹, Jun Li²

¹Nursing college, Binzhou Medical University, Yantai, Shandong, China.

|August 20, 2014

Summary

Susceptibility-weighted imaging effectively detects intracranial hemorrhage in heat stroke patients. This imaging technique may also help predict patient outcomes, identifying those at higher risk of severe complications or death.

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A Preclinical Model of Exertional Heat Stroke in Mice

A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

Area of Science:

Neurology
Radiology
Emergency Medicine

Background:

Heat stroke is a critical medical emergency characterized by severe hyperthermia.
Complications include disseminated intravascular coagulation and potential neurological damage.

Purpose of the Study:

To evaluate the utility of susceptibility-weighted imaging (SWI) in identifying intracranial hemorrhage (ICH) post-heat stroke.
To determine if SWI can aid in predicting prognosis for heat stroke patients.

Main Methods:

Eight heat stroke patients with Glasgow Coma Scale scores of 3-9 underwent MRI.
Susceptibility-weighted imaging was performed 2-5 days after heat stroke onset using a 1.5 T scanner.

Main Results:

SWI detected punctate hemorrhages in the brainstem, corona radiata, and frontal lobe in three patients.
Two of these patients died within 25 days; the third entered a persistent vegetative state and died later.
The five patients without detected hemorrhages showed gradual recovery with residual cerebellar dysfunction.

Conclusions:

Heat stroke can lead to life-threatening intracranial hemorrhages.
Susceptibility-weighted imaging is a valuable tool for detecting these hemorrhages.
SWI shows potential for prognostication in heat stroke patients.