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A vanishing lymphoma in the cheek
Douglas Farquhar1, Joseph Sobanko, Kimberly Williams
1Department of Otorhinolaryngology - Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pa., USA.
Summary
A rare case of follicular lymphoma in the head and neck vanished after steroid treatment, presenting diagnostic challenges. This steroid-sensitive lymphoma highlights the importance of considering medication history in diagnosis.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- A 66-year-old woman presented with a cheek mass.
- The mass initially responded completely to oral steroid treatment.
Observation:
- Multiple biopsies were inconclusive.
- MRI showed a large mass, which became undetectable after steroids.
- A subsequent biopsy confirmed follicular lymphoma.
Findings:
- Follicular lymphoma, a type of non-Hodgkin lymphoma, is known for steroid sensitivity.
- This case represents a 'vanishing' lymphoma in the head and neck, a presentation previously undocumented.
- The steroid-induced resolution posed significant diagnostic difficulties.
Implications:
- Steroid-sensitive lymphomas can present as 'vanishing' masses, complicating diagnosis.
- Discontinuing steroids before biopsy may be crucial for accurate lymphoma diagnosis in such cases.
- This case underscores the need for thorough patient history, including medication use, in head and neck oncology.
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