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Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Cardiac Catheterization I: Pre-Procedure Overview01:28

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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Mitral Stenosis III: Medical Management01:26

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Related Experiment Video

Updated: Apr 25, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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[Transcatheter aortic valve replacement].

Yoshiki Sawa1

  • 1Department of Cardiovascular Surgery, Osaka University, Suita, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 21, 2014
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) offers promising early results for severe aortic stenosis patients in Japan. Ongoing device and technique improvements aim to reduce complications and expand TAVR use to lower-risk individuals.

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Area of Science:

  • Cardiovascular medicine
  • Interventional cardiology
  • Medical device technology

Context:

  • Transcatheter aortic valve replacement (TAVR) has seen rapid global adoption for severe aortic stenosis (AS).
  • In Japan, TAVR adoption began in 2013, with approximately 400 cases performed to date.
  • Our institute has performed 164 TAVR cases since 2009, achieving a 1.2% 30-day mortality rate.

Purpose:

  • To review the evolution of TAVR devices and techniques in Japan.
  • To highlight the management of TAVR-related complications.
  • To discuss expanding indications and future directions for TAVR.

Summary:

  • Early TAVR outcomes in Japan are satisfactory, but complications like paravalvular leak and stroke occur.
  • Second-generation devices and improved implantation techniques have reduced complication rates.
  • Midterm results show good prosthetic valve function, durability, and improved quality of life.

Impact:

  • Technical advancements are enhancing TAVR safety and efficacy.
  • TAVR is increasingly used for special indications and shows potential for intermediate-risk patients.
  • Future TAVR expansion to lower-risk populations is anticipated, pending further clinical trial data.