Related Experiment Video
Updated: Apr 25, 2026

08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
3.7K
[Percutaneous edge-to-edge repair using the MitraClip system]
Takashi Matsumoto1, Saibal Kar
1Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 21, 2014
Summary
The MitraClip system offers a minimally invasive treatment for mitral regurgitation (MR). This catheter-based therapy shows safety and efficacy for degenerative and functional MR, with widespread adoption.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Context:
- Mitral regurgitation (MR) is a significant cardiac condition.
- The MitraClip system provides a percutaneous edge-to-edge repair option.
- Established safety and efficacy in clinical studies for degenerative and functional MR.
Purpose:
- To review the MitraClip system for mitral regurgitation (MR).
- To describe the concept and procedural steps of MitraClip therapy.
- To present clinical trial results and current US status.
Summary:
- The MitraClip system is a catheter-based therapy for moderate-to-severe or severe mitral regurgitation (MR).
- It has demonstrated safety and efficacy in patients with both degenerative and functional MR.
- The therapy received CE mark in 2008 and US FDA approval in 2013 for specific indications.
Impact:
- Represents a significant advancement in transcatheter structural heart interventions.
- Offers a less invasive alternative to traditional surgery for eligible MR patients.
- Around 12,000 patients have undergone MitraClip therapy globally, indicating its clinical significance.

