Related Experiment Video
Updated: Apr 25, 2026

08:15
Reverse Dissection and DiceCT Reveal Otherwise Hidden Data in the Evolution of the Primate Face
Published on: January 7, 2019
6.4K
Evolution of the central sulcus morphology in primates
William D Hopkins1, Adrien Meguerditchian, Olivier Coulon
1Neuroscience Institute, Georgia State University, Atlanta, Ga., USA.
Brain, Behavior and Evolution
|August 21, 2014
Summary
Humans and great apes possess a distinct motor-hand area. However, this brain region is relatively smaller in humans compared to great apes, despite its evolutionary significance.
Area of Science:
- Neuroscience
- Primatology
- Evolutionary Biology
Background:
- The central sulcus (CS) delineates brain regions for motor and sensory functions.
- The precentral gyrus's motor-hand area is crucial for human hand representation.
- Hand evolution is significant in primate history.
Purpose of the Study:
- To investigate the evolutionary changes in the primate motor-hand area.
- To compare the size and folding patterns of the central sulcus surface area across primate species.
Main Methods:
- Magnetic resonance imaging (MRI) was used to analyze the central sulcus surface area.
- The study included 131 primates: Old World monkeys, apes, and humans.
- Comparative analysis of relative size and cortical folding patterns was performed.
Main Results:
- Humans and great apes exhibit a well-defined motor-hand area, indicated by central sulcus depth variations.
- Great apes possess larger central sulcus surface areas relative to Old World monkeys.
- Humans have smaller absolute and adjusted surface areas for the motor-hand area compared to great apes.
Conclusions:
- The evolution of the motor-hand area shows distinct patterns in humans and great apes.
- Despite its importance, the human motor-hand area is relatively reduced compared to great apes.
Related Concept Videos
Synteny and Evolution
2.9K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
2.9K
Cerebrum: Anatomical Overview I
5.7K
The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...
5.7K
Sutures of the Skull
13.8K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
13.8K
Neurulation
40.1K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
40.1K
Anatomy of the Brain: Major Regions
11.3K
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
11.3K
Cerebrum: Anatomical Overview II
4.9K
Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
4.9K

