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Multiple microemboli after disintegration of clot during thrombolysis for acute myocardial infarction
P J Stafford1, C J Strachan, R Vincent
1Department of Cardiology, Royal Sussex County Hospital, Brighton.
BMJ (Clinical Research Ed.)
|November 25, 1989
Abstract:
Seven of 475 consecutive patients treated with thrombolysis for acute myocardial infarction had severe embolic complications that were believed to be caused by disintegration of pre-existing clot. Three patients had symptoms that persisted for many weeks, and five died. Any potential site of pre-existing blood clot within the vascular system, notably an enlarged left atrium, ventricular aneurysm, or aortic aneurysms, should be regarded as a contraindication to treatment with thrombolytic agents.