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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Related Experiment Video

Updated: Apr 25, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Mesenteric fibromatosis.

Poras Chaudhary¹

¹Lady Hardinge Medical College and associated Dr RML Hospital, New Delhi, India, drporaschaudhary@yahoo.com.

International Journal of Colorectal Disease

|August 21, 2014

Summary

This summary is machine-generated.

Mesenteric fibromatosis, a rare intra-abdominal tumor, presents diagnostic and treatment challenges due to its high recurrence rate. This review covers current knowledge and case studies on this uncommon condition.

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Multimodality Diagnosis of Mesenteric Ischemia

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Published on: July 21, 2023

Area of Science:

Oncology
Gastroenterology
Surgical Pathology

Background:

Mesenteric fibromatosis is a rare, locally invasive intra-abdominal tumor.
It is characterized by a high rate of recurrence and poses diagnostic and therapeutic challenges.
Tumors often present as painless masses, though they can be asymptomatic.

Purpose of the Study:

To present current knowledge on mesenteric fibromatosis.
To share experience from four patient cases.
To conduct a comprehensive literature review on mesenteric fibromatosis.

Main Methods:

Literature review of mesenteric fibromatosis.
Analysis of four clinical cases.
Synthesis of existing data on diagnosis and treatment.

Main Results:

Mesenteric fibromatosis is rare, locally invasive, and has a high recurrence rate.
Surgical excision with wide margins is the primary treatment; medical therapy is for inoperable/recurrent cases.
Limited extensive research exists, with many case reports detailing unusual presentations.

Conclusions:

Mesenteric fibromatosis requires specialized diagnostic and therapeutic approaches.
Further research is needed to establish clear treatment guidelines.
This review consolidates current understanding and clinical experience with mesenteric fibromatosis.