Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

7.2K
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
7.2K
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

4.1K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
4.1K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

922
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
922
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

3.1K
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
3.1K
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

1.3K
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
1.3K
Ventilatory Modes01:14

Ventilatory Modes

2.3K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-order simulation of geological domains and effects on stochastic long-term planning of mining complexes.

Mining technology (Abingdon, Eng.)·2026
Same author

Patient self-inflicted lung injury - does it really exist?

Current opinion in critical care·2025
Same author

GRADE Guidance 44: strategies to enhance the utilization of randomized and non-randomized studies in evidence syntheses of health interventions.

Journal of clinical epidemiology·2025
Same author

Recommendations to Enable Broader Use of Real-World Evidence to Inform Decision-Making Throughout Pharmacovigilance Signal Management.

Pharmacoepidemiology and drug safety·2025
Same author

Association Between β-Adrenoreceptor Agonists and Antagonists and Parkinson's Disease: Systematic Review and Meta-Analysis.

Pharmacoepidemiology and drug safety·2025
Same author

Modeling conditional distributions of neural and behavioral data with masked variational autoencoders.

Cell reports·2025
Same journal

Monographic Issue on New Concepts in Acute Exacerbations of COPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Bidirectional Clinical Interactions among Exacerbations and Comorbidities in COPD: A Narrative Review.

Seminars in respiratory and critical care medicine·2026
Same journal

Radiological Approach to Severe Respiratory Infections and Pulmonary Complications in Immunocompromised Patients.

Seminars in respiratory and critical care medicine·2026
Same journal

Two Sides of the Same Smoke: Decoding Respiratory Bronchiolitis-Associated Interstitial Lung Disease and Alveolar Macrophage Pneumonia.

Seminars in respiratory and critical care medicine·2026
Same journal

Role of Vaccination in the Prevention of ECOPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Pharmacological Treatment of AECOPD New Perspectives.

Seminars in respiratory and critical care medicine·2026
See all related articles

Related Experiment Video

Updated: Apr 25, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

602

Weaning from mechanical ventilation.

Hameeda Shaikh1, Daniel Morales2, Franco Laghi1

  • 1Division of Pulmonary and Critical Care, Edward Hines, Jr. Veterans Affairs Hospital, Hines, Illinois.

Seminars in Respiratory and Critical Care Medicine
|August 21, 2014
PubMed
Summary
This summary is machine-generated.

Safely discontinuing mechanical ventilation (MV) requires a careful approach. A three-step diagnostic strategy helps intensivists reduce risks associated with delayed weaning and premature extubation in critically ill patients.

More Related Videos

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
04:16

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide

Published on: January 30, 2026

1.1K
Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.3K

Related Experiment Videos

Last Updated: Apr 25, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

602
Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
04:16

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide

Published on: January 30, 2026

1.1K
Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.3K

Area of Science:

  • Critical Care Medicine
  • Pulmonary Physiology
  • Intensive Care Unit Management

Background:

  • Mechanical ventilation (MV) is a life-saving intervention for critically ill patients but carries risks.
  • Delayed discontinuation of MV can negatively impact patient outcomes.
  • Premature weaning or extubation attempts can lead to significant respiratory distress and clinical setbacks.

Purpose of the Study:

  • To outline a diagnostic strategy for optimizing the process of weaning patients from mechanical ventilation.
  • To emphasize the importance of a systematic approach to reduce complications associated with MV discontinuation.
  • To highlight the critical role of clinical decision-making in interpreting weaning assessments.

Main Methods:

  • A three-step diagnostic strategy for weaning from MV is proposed.
  • This strategy includes: 1. Measurement of weaning predictors. 2. A trial of unassisted breathing (T-tube trial). 3. A trial of extubation.
  • The approach necessitates a thorough understanding of each diagnostic test and clinical decision-making principles.

Main Results:

  • The proposed strategy aims to mitigate the risks of both delayed weaning and premature extubation.
  • Successful implementation requires clinicians to master the interpretation of diagnostic tests related to respiratory function.
  • Individualized patient care based on physiological principles is crucial for effective weaning.

Conclusions:

  • A structured, three-step diagnostic approach can improve the safety and efficiency of mechanical ventilation weaning.
  • Effective weaning management demands sophisticated, individualized care and analytical interpretation of patient data.
  • Applying physiological principles to mechanical ventilation weaning offers significant potential for improving patient outcomes in the intensive care unit.