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A framework for understanding shared substrates of airway protection
Michelle Shevon Troche1, Alexandra Essman Brandimore1, Juliana Godoy2
1Department of Speech, Language, and Hearing Sciences, University of Florida, Gainesville, FL, USA.
Journal of Applied Oral Science : Revista FOB
|August 21, 2014
Summary
Effective airway protection relies on swallowing and coughing. This review proposes a new framework for understanding the shared neural control of these protective reflexes, aiming to improve patient outcomes.
Area of Science:
- Neuroscience
- Physiology
- Respiratory Medicine
Background:
- Deficits in airway protection negatively impact health and quality of life.
- Effective airway protection involves coordinated swallowing and coughing reflexes.
- These protective mechanisms share overlapping neural control pathways.
Purpose of the Study:
- To present a novel framework for understanding the shared neural substrates of airway protection.
- To synthesize existing literature supporting this unified model.
- To provide a basis for future research on airway protective deficits.
Main Methods:
- Literature review of existing studies on swallowing and cough control.
- Adaptation of Eccles' model of cough (2009) by Hegland et al. (2012).
- Synthesis of findings to support a shared control framework.
Main Results:
- Significant overlap identified in the neural control mechanisms for swallowing and cough.
- A novel framework integrating swallowing and cough as components of airway protection is proposed.
- This framework highlights shared neural substrates.
Conclusions:
- A unified framework for airway protection, encompassing swallowing and cough, is presented.
- This model facilitates hypothesis generation for future research.
- Advancing understanding of shared substrates can improve outcomes for individuals with airway protective deficits.
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