Related Experiment Videos

Mutagenicity arising from boiled rice on treatment with nitrous acid

H Hayatsu¹, T Hayatsu

¹Faculty of Pharmaceutical Sciences, Okayama University.

Japanese Journal of Cancer Research : Gann

|November 1, 1989

Abstract:

When an aqueous homogenate of boiled rice was treated with nitrous acid at pH 3, direct-acting mutagens were formed. The presence of the mutagens was demonstrated by isolating the mutagenic fractions through blue-rayon adsorption, a method used to extract polycyclic compounds, and subsequent high-performance liquid chromatography (HPLC). The mutagens were active in Salmonella typhimurium TA100 and TA98 without metabolic activation. Several different mutagens were formed, as judged from the HPLC profile.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

Pseudouridine, an antimutagenic substance in beer towards N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2002

Inhibition of DNA adduct formation and mutagenic action of 3-amino-1-methyl-5h-pyrido[4,3-b]indole by chlorophyllin-chitosan in rpsL transgenic mice.

Japanese journal of cancer research : Gann·2001

Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila.

Mutation research·2001

Somatic-cell mutation induced by UVA and monochromatic UV radiation in repair-proficient and -deficient Drosophila melanogaster.

Photochemistry and photobiology·2001

Identification of mutagenic heterocyclic amines (IQ, Trp-P-1 and AalphaC) in the water of the Danube river.

Mutation research·2001

Oxidative damage and induced mutations in m13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation.

Mutagenesis·2000

See all related articles