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An iridoid glucoside and the related aglycones from Cornus florida
Yangqing He1, Jiangnan Peng, Mark T Hamann
1Department of Applied Chemistry, College of Science, Xi'an University of Technology , Xi'an 710054, People's Republic of China.
Abstract:
A new iridoid glucoside, cornusoside A (1), and four new natural product iridoid aglycones, cornolactones A-D (2-5), together with 10 known compounds were isolated from the leaves of Cornus florida. The structures of compounds 1-5 were established by interpretation of their spectroscopic data. Cornolactone B (3) is the first natural cis-fused tricyclic dilactone iridoid containing both a five- and a six-membered lactone ring. A biosynthesis pathway is proposed for cornolactones C (4) and D (5), the C-6 epimers of compounds 1-3.
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