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[Analysis on the relationship between adolescent myopia and serum sex hormone]
Hongli Xie1, Xinjie Mao, Haihong Yang
1The Institute for Public Policy and Social Development, Wenzhou Medical University, Wenzhou 325035, China.
Objective:
To investigate the quantitative changes of the serum sex hormone levels in juvenile myopia patients.
Methods:
In January 2013, investigation of Wenzhou middle school 822 adolescents, including 432 male patients and 390 female patients were involved in the study Visual acuity ≥ 5 was set as the normal value. The subjects were divided into two groups, the myopia group and the non-myopia group. Chemiluminescence immunoassay analyzer was used to detect the subjects' sex hormone concentration of estradiol (E2), testosterone (T), follicle stimulating hormone (FSH) and luteinizing hormone (LH).
Results:
The follicle stimulating hormone and luteinizing hormone of the female patients were significantly higher than those of male counterparts (P < 0.01); among the two groups consisting female myopia and non-myopia patients, a significant difference in luteinizing hormone and follicle stimulating hormone was shown (P < 0.05); the distinct differences in the level of luteinizing hormone and testosterone level showed in the male myopia group and non-myopia group were of outstanding statistics significance (P < 0.01), showing the result that the level of sex hormone in myopia group was higher than that in the non-myopia group.
Conclusion:
A close relationship perhaps between the level of sex hormone with gender differences and juvenile myopia is confirmed.
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