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Bullous pemphigoid after bilateral forefoot surgery
1Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK dishan.singh@aol.com.
Foot & Ankle Specialist
|August 22, 2014
Summary
Bullous pemphigoid, an autoimmune blistering disease, can occur in elderly patients following surgery. Early diagnosis by specialists is crucial for persistent post-surgical skin eruptions.
Area of Science:
- Dermatology
- Autoimmune Blistering Diseases
Background:
- Bullous pemphigoid (BP) is a chronic autoimmune blistering disease predominantly affecting the elderly.
- It is characterized by antibodies targeting hemidesmosomes in the basement membrane zone.
Observation:
- A case report details a 76-year-old woman who developed blisters on her forefeet two weeks after bilateral forefoot surgery.
- The clinical presentation mimicked bullous contact dermatitis at the surgical sites.
Findings:
- Histological and immunofluorescence studies confirmed the diagnosis of bullous pemphigoid.
- The review highlights that surgical wounds can occasionally trigger or be associated with bullous pemphigoid.
Implications:
- Foot and ankle specialists must consider bullous pemphigoid in the differential diagnosis of persistent, blistering eruptions at surgical sites.
- Awareness of this association can lead to earlier diagnosis and appropriate management of bullous pemphigoid in post-operative patients.
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