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In vitro granulocyte aggregation

S Antonsen1, J M Beyer

  • 1Department of Clinical Chemistry and Medical Rheumatology, Odense University Hospital, Denmark.

Granulocyte aggregation in EDTA-blood from a patient with rheumatoid arthritis is described. The phenomenon was observed three times within a 10-month period. The blood leukocyte count in a Coulter Counter decreased approximately 30% within 6 h, without resulting in overt leukopenia. Simultaneously, increasing numbers of granulocyte aggregates turned up in smears. There were no indications of thrombocytes being involved in the phenomenon.

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