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Updated: Apr 25, 2026
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Published on: July 17, 2012
Computed tomography colonography: ready for prime time for colon cancer screening?
Parth J Parekh1, Rouzbeh Shams, E C Oldfield
1*Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tulane University, New Orleans, LA †Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA ‡Eastern Virginia Medical School, Norfolk, VA §Department of Gastroenterology, Scripps Health, San Diego, CA ∥Department of Internal Medicine, Gastroenterology Division, Eastern Virginia Medical School, Norfolk, VA.
Abstract:
In 2008, results from the landmark American College of Radiology Imaging Network (ACRIN) trial provided evidence supporting the use computed tomography colonography (CTC) as a comparable alternative to colonoscopy for colorectal cancer (CRC) screening. Subsequently, however, the United States Preventive Task Force decided against a recommendation in support of CTC for CRC screening. Following soon after, the Centers for Medicare and Medicaid Services (CMS) made noncoverage decision for the use of CTC in CRC screening. Since that decision, there have been a number of publications on CTC and CRC screening with a strong push from the radiology community to reassess CTC as a viable option. The purpose of this review was to address focused questions concerning the use of CTC in CRC screening, through an analysis of the available scientific evidence in an effort to provide recommendations for clinicians, patients, and payors who may evaluate the role of CTC for CRC screening.
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